A: Safety in cryogenic storage tank design is ensured through multiple approaches: adherence to engineering codes (e.g., ASME, API), incorporation of pressure relief systems to prevent overpressure, proper venting for boil-off gases, use of materials with sufficient low-temperature strength and toughness, and insulation to control heat ingress and prevent rapid temperature changes. Additional safety measures include leak detection systems, secondary containment, and emergency response planning. Welding and fabrication processes must follow stringent quality controls to avoid defects. Periodic inspection and maintenance are critical once the tank is in service. Regulatory guidance can be found at OSHA's Cryogenic Safety webpage: https://www.osha.gov/cryogenic-safety